H2N2V1, Main, Exploration, bibRecord, 001282

A vaccine manufacturer’s approach to address medical needs related to seasonal and pandemic influenza viruses

Identifieur interne : 001282 ( Main/Exploration ); précédent : 001281; suivant : 001283

A vaccine manufacturer’s approach to address medical needs related to seasonal and pandemic influenza viruses

Auteurs : Benoit Baras ; Nancy Bouveret ; Jeanne-Marie Devaster ; Louis Fries ; Paul Gillard ; Roland S Nger ; Emmanuel Hanon

Source :

Influenza and Other Respiratory Viruses [ 1750-2640 ] ; 2008.

RBID : PMC:2710798

Abstract

Abstract Vaccination is considered to be one of the most effective tools to decrease morbidity as well as mortality caused by influenza viruses.

For the prevention of seasonal influenza, Fluarix™ and FluLaval™ have been marketed since 1987 and 1992, respectively. Both vaccines have consistently been shown to meet or exceed the regulatory criteria for immunogenicity against the three strains H1N1, H3N2 and B, have a good safety profile, and are recommended for vaccinating children and adults of all ages.

For the prevention of pandemic influenza, GlaxoSmithKline (GSK) has obtained licensure of a pre‐pandemic vaccine, Prepandrix™. This split‐virus H5N1 adjuvanted with AS03, a proprietary oil‐in‐water emulsion‐based adjuvant system, has demonstrated broad immunity against drifted H5N1 strains and has been shown to be effective in preventing mortality and viral shedding in animal studies.

The influenza vaccine portfolio of GSK addresses specific medical needs related to seasonal or pandemic influenza viruses, which remain an important public health threat worldwide.

Url:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2710798

DOI: 10.1111/j.1750-2659.2008.00054.x
PubMed: 19453402
PubMed Central: 2710798

Affiliations:

Le document en format XML

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<front><div type="abstract" xml:lang="en"><p><bold>Abstract</bold>
 Vaccination is considered to be one of the most effective tools to decrease morbidity as well as mortality caused by influenza viruses.</p>
<p>For the prevention of seasonal influenza, <italic>Fluarix</italic>
<italic>™</italic>
 and <italic>FluLaval</italic>
™ have been marketed since 1987 and 1992, respectively. Both vaccines have consistently been shown to meet or exceed the regulatory criteria for immunogenicity against the three strains H1N1, H3N2 and B, have a good safety profile, and are recommended for vaccinating children and adults of all ages.</p>
<p>For the prevention of pandemic influenza, GlaxoSmithKline (GSK) has obtained licensure of a pre‐pandemic vaccine, <italic>Prepandrix</italic>
<italic>™</italic>
. This split‐virus H5N1 adjuvanted with AS03, a proprietary oil‐in‐water emulsion‐based adjuvant system, has demonstrated broad immunity against drifted H5N1 strains and has been shown to be effective in preventing mortality and viral shedding in animal studies.</p>
<p>The influenza vaccine portfolio of GSK addresses specific medical needs related to seasonal or pandemic influenza viruses, which remain an important public health threat worldwide.</p>
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A vaccine manufacturer’s approach to address medical needs related to seasonal and pandemic influenza viruses

A vaccine manufacturer’s approach to address medical needs related to seasonal and pandemic influenza viruses

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